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T D Han Selected Research

1- (1- (4- fluoro- 2- (2- oxopyrrolidin- 1- yl)phenyl)- 3- oxopiperidin- 4- ylcarbamoyl)cyclohexyl furan-2-carboxylic acid amide

8/2006An orally active cathepsin K inhibitor, furan-2-carboxylic acid, 1-{1-[4-fluoro-2-(2-oxo-pyrrolidin-1-yl)-phenyl]-3-oxo-piperidin-4-ylcarbamoyl}-cyclohexyl)-amide (OST-4077), inhibits osteoclast activity in vitro and bone loss in ovariectomized rats.

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T D Han Research Topics

Disease

1Carcinoma (Carcinomatosis)
02/2016
1Osteoporosis
08/2006
1Bone Resorption
08/2006

Drug/Important Bio-Agent (IBA)

1Mitogen-Activated Protein KinasesIBA
02/2016
1Docetaxel (Taxotere)FDA Link
02/2016
1Pharmaceutical PreparationsIBA
08/2006
1PapainIBA
08/2006
1Parathyroid Hormone (Parathormone)IBA
08/2006
1Cathepsin KIBA
08/2006
11- (1- (4- fluoro- 2- (2- oxopyrrolidin- 1- yl)phenyl)- 3- oxopiperidin- 4- ylcarbamoyl)cyclohexyl furan-2-carboxylic acid amideIBA
08/2006
1Cysteine Proteases (Cysteine Protease)IBA
08/2006
1Alkaline PhosphataseIBA
08/2006